Homology-directed repair: How the cell edits DNA after a CRISPR-induced break

Talk Overview

Sometimes DNA breaks because of insults like x-rays, UV rays, or genetic scissors (e.g., CRISPR-Cas9). DNA breakage can have serious consequences if not corrected. Luckily, the cell has mechanisms to repair those breaks, including one known as homology-directed repair. In this fun animated clip, scientists describe how homology-directed repair works in an accessible way. You’re left with a haiku to better remember it.

This clip was taken from Human Nature, the documentary which explores the discovery and future implications of the CRISPR-Cas9 genome editing technology.

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